
| Pair Name | Palmatine, Doxorubicin | ||
| Phytochemical Name | Palmatine (PubChem CID: 19009 ) | ||
| Anticancer drug Name | Doxorubicin (PubChem CID: 31703 ) | ||
| Structure of Phytochemical |
Download
2D
MOL
3D
MOL
|
||
| Structure of Anticancer Drug |
Download
2D
MOL
3D
MOL
|
||
| Pair Name | Palmatine, Doxorubicin | |||
| Disease Info | [ICD-11: 2C60] | Breast cancer | Investigative | |
| Biological Phenomena | Induction-->Proliferation | |||
| In Vitro Model | MCF-7 | Invasive breast carcinoma of no special type | Homo sapiens (Human) | CVCL_0031 |
| T-47D | Invasive breast carcinoma of no special type | Homo sapiens (Human) | CVCL_0553 | |
| ZR75-1 | Invasive breast carcinoma of no special type | Homo sapiens (Human) | CVCL_0588 | |
| Result | Our studies suggest that PLT can be a potential candidate agent for preventing and treating breast cancer. | |||
| No. | Title | Href |
|---|---|---|
| 1 | Palmatine, a Bioactive Protoberberine Alkaloid Isolated from Berberis cretica, Inhibits the Growth of Human Estrogen Receptor-Positive Breast Cancer Cells and Acts Synergistically and Additively with Doxorubicin. Molecules. 2021 Oct 15;26(20):6253. doi: 10.3390/molecules26206253. | Click |